How many sensitive issues did this movie really touch in your opinion?

If you were to count it? And by that I mean both objectively, and subjectively, including ones that may have ALWAYS been that and ones that may have ESPECIALLY become that or became VISIBLY as that in our 21st Century digital age? "The Skin I Live In" (2011), by Pedro Almodovar and starring Antonio Banderas?

Including rape and sexual abuse (even if some audiences DID question if that scene was it, and its not to be chalked down to "r-e culture" but perhaps the way that scene was filmed etc although many also agreed it was it), to the theme of vengeance on the perpetrator, to turning the male against his will into a woman and to be used as various kinds of guinea pig in medical research and vengeance? The existence of a crazy brother who also happens to be a rapist? Questionable medical ethics? Mental illness? Revenge? Murder and death? Kidnapping and forced imprisonment?

Transsexuality and also forcefully changing ones gender? Family loss? Suicide? Painful memories etc?

Granted at least ONE of those topics (and I am not judging, but just take a look at both the reviews here and elsewhere, including negative ones) is no doubt considered arguably THE most sensitive one, and I don't think that in today's day and age you have to be a genius with an IQ of above 130 to guess which one it is, although it helps (as certain folks here still ARGUE about it, making it also the subject of inevitable controversy, but it could also have been "attempted rape" and some kind of neglect but OK if filmmaker says it was it then it was it) to be at least "fairly intelligent". But it does have OTHER topics to it, sensitive issues, in what is essentially a thriller/horror/drama film with elements of science fiction or at least exaggerated science to it.

But anyways, all this talk aside, and it is a FILM we're discussing after all, how many sensitive issues and themes does this movie have in your opinion? I counted at least 6, you? Thank you.