Charlize Theron as Cheetah in Wonder Woman 2?
To me this is too good an idea to pass up. Charlize was the star of Jenkins' first movie, Monster, which earned her an Oscar. Now she is a bigger action star than ever. She can play the rich, high-class, aristocrat side of the Cheetah who can charm Diana as well as the feral, violent, cursed side who can physically threaten Wonder Woman. And her body is in tip-top shape to wear the form-fitting Cheetah skin. We know that superhero movies should have a villain that looks eye-catching and original. We haven't seen anything that looks quite like Cheetah in superhero films to date.
We see Diana's modern headquarters is filled with artifacts in Wonder Woman. The Cheetah is a hunter of rare artifacts. She could be searching for the legend of Themyscira and trying to use Diana to get to it. Then Diana finds out how many people Cheetah is killing along the way to get what she wants as well as to satisfy the bloodlust of her curse. Here's some concept art:
https://image.ibb.co/n3srdQ/cheetahcharlize.jpg