Hope vs. ER
I know when they both first came out, everyone (including myself) was puzzled why 2 medical shows would go head to head in the same timeslot. That obviously didn't last long.
Now, I won't deny ER is a top notch show, even now, however I would contend that in the first season of both shows, Hope was better. Mandy Patakin is just an incredible actor, and the ensemble cast was terrific in year 1. Unfortunately, after Mandy left, ER jumped far ahead, and when Mandy came back in '99, it was too late.