Another one that seems ripe for an update...
Along with Colossus: The Forbin Project, this is another of those 60s era sci-fi movies that seems like some Hollywood studio would update.
In these days of COVID and pandemics in the news, a re-make could focus on a team trying to learn more about a highly lethal super-virus or super-bacterial infection that has the potential to kill off the human race by chasing it down in the body of a carrier.
Or maybe trying to battle intelligent nanobots that have been released into a high ranking government official as part of some elaborate terrorist plot.