This movie really should be remade... who would be a good cast?

With our more indepth knowledge of the human anatomy and the inner wonders and workings of the human body, combined with the nearly infinite possibilities afforded by the advances in special fx, CGI, et al, I think that Fantastic Voyage would be a PRIME candidate for a remake.

I mean, how many old and crummy 70's TV shows can they redo into movies? And for cryin' out loud, we're getting a movie of Fat Albert??? They're talking about a big-screen version of "F Troop"???? They are remaking movies that just came out in the late 70's or 80's... come on, folks, let's take a look at some of the promising SciFi flicks of the 1960's and imagine the possibilities!

Of course, if they were to remake it, I'm sure that Hollywood would probably ruin it anyway. The effects would be great but they'd put in somebody like Reese Witherspoon or (shudder) Jennifer Lopez to play the role of Cora Peterson. Vin Diesel would be Grant... or maybe Keanu Reeves. (Major shudder)

Who do you think would be a good cast?