Lab security protocols
Their lab security was kind of strange.
I would have expected them to be totally robotic in a closed box, not a glove box. This means it can have a solid mechanical barrier.
The box should be capable of an emergency sequence where it can get heated to 3000 degrees and then vented directly to open space. The lab itself should have an emergency purge function that vents it to outer space. Then finally, explosive bolts to jettison the entire lab and thrusters to get it into the highest possible orbit.
I don't think any of their thrusting systems had the delta-v to get them past lunar orbit, that part in the film seemed dubious but didn't ruin it.