Not even close to the real thing
I have met real life Karen's. They're usually blonde, well-to-do and bitchy. They're passive aggressive but not afraid to chew you out once you step over their line. This usually involves them screaming in your face and threatening to call their husband or lawyer. In terms of their racism it's usually manifested in reporting the first black person they see pacing through the neighbourhood in 3..2..1 seconds.
The movie's choice of a ''Karen'' is an odd one. This is not how a Karen looks or acts.