It affected me, but...
...I didn't like it.
My parents are divorced and some of the scenes from the film were strong reminders of that time (not letting Dad into the house he used to live in, custody issues, parents dating other people, etc), so much so that I cried afterward. But it wasn't a good, wow-that-was-amazing movie cry, I felt horrible and miserable. I can understand if that was the point of the movie, to evoke those kinds of feelings, but so many people LOVE this movie and it's so highly rated. My boyfriend's parents are together and the movie was lost on him.
I don't think that personal connections are enough to make a movie good. Especially a comedy (the hell??).