Was Mary Anne's (Charlize Theron's) character under Al Pacino's (Milton's) spell?
Did he put her under his demonic spell literally at that "party" and was this was what caused her mental deterioration as well as those nightmares and whatnot?
Even before he intimately violated her (and even in that process, it was also a supernatural attack, correct?) and caused her later to SPOILERS - commit suicide at that hospital.
Do you think he put her under the spell as well? I thought so.