Why the Ending Doesn't Work
Blowing it up won't kill it. There were obviously chunks of it all over the place, and as we know their first attempt to put it back in the ocean a piece got cut off and lived on its own.
Now there are like thousands of little pieces that'll become little monsters and infect sharks, or other dangerous sea-life. Since it has all that "absorbed intelligence" could you imagine a shark with all those people's knowledge, or some octopus growing 100x bigger than normal?
Hell Deep Blue Sea already tackled the "smart shark" theory. Another not so good movie...