spoilers
(Unless there was an addictive element to the drug) word would have got around that he drug would make you crazy after prolonged use. Thus the workers would have shunned it.
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Frankly, once the casualties kept piling up the most economic thing for the Company to do would be to just stop the drug shipments. It can't be cheap to train these guys and ship them off to Outer Space and then have to keep training replacements because they keep killing themselves.
Eventually, someone would think "The profits we're making aren't offsetting the money we're losing from having to keep hiring people, shipping them out and paying insurance money to the families of the dead ones."
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