'Barney Quill was my father'
In response to a question by prosecution in court asked of Mary Pilant, "Were you Barney Quill's mistress?" Prosecution was so sure they were romantically involved, he stepped in the one mudpile everybody knows you have to watch out for: "never ask the witness a question to which you don't know the answer and which you are not sure how they will answer".
What a spectacular brief moment of acting by the great George C. Scott in sudden realization that all his work to convict was suddenly doomed.