Nathan was Will's nurse, had been for nearly two years, Lou was employed as a paid companion/assistant, to provide general help, cooking, feeding, company, driving. However in the book she ends up doing some "nursing" stuff too, by the time Will goes to her birthday dinner, for example, she says that she has learned to change his catheter bag and tubes, and is not longer bothered by it. So she did some basic health care when Nathan was not available.
His family had the nursing part covered already, they wanted to hire someone for companionship mostly, Will was feeling very depressed and also deeply humilated by his need of physical assistance, his parents wanted Lou to be something else to Will, someone Will could feel more comfortable with, someone in whose company he could feel less a "patient" and more a "person/man".
That's the idea I got anyway.
In the movie Will physical needs and health problems were given less space and attention than in the book.
"Please, if you are trying to convert me, this isn't a good time"
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