Resembles Bipolarity, or even Autism... rather than Depression
If the theme of this film was truly about Depression... then Von Trier was certainly overstating things... I'll buy that it was a film resembling Depression, from an Autistic mind.
Every actor in this film seemed be missing their "soul" (if you care to believe that human beings have a soul)... probably from the "wooden" and "emotionless" performances (except when experiencing 'melancholy'... which is again overstated), no doubt demanded by Von Trier... it truly came across like "pretentious drivel"...
every actor seemed to either be emotionally damaged or seemed to take immense satisfaction in "kicking someone when they are down"... completely overstating the supposed 'themes' of this film.
It would make more sense if it was more about the difficulties in being around other people... more like autistics or people who are bipolar.