How many of them will be turned into lesbians?

The Lefties were probably drooling at the mouth wanting to turn Buttercup into a hardcore, feminist lesbian. You can't be a tomboy in [current year] media without being a lesbian.

I imagine Blossom might be able to escape being hetero... maybe. She might end up being bi.

Just to shock and turn-off normal viewers they'll also probably turn Bubbles into a lesbian, too. But she'll probably have to have some awakening where she realizes she's no longer attracted to men in some cringe-inducing sub-plot.

I would be thoroughly shocked if all of them were straight, but even the CW's reboot of Charmed saw some of the trio being turned gay and being black-washed. So there's probably no hope for the Powerpuff girls escaping the CW's degenerate Liberal Progressive wrath.