Plot synopsis.
From filmick.org:
As film ick reported in early December, Penelope Cruz and Pedro Almodovar are to reteam for the director's next movie, a revenge drama. What wasn't known at the time - and which I'm hearing now, as Variety announce the project formally and the world lights up with discussion of it's plot and characters - is just what role Ms. Cruz is to play.share
This one might be quite a challenge for her. Apparently, the film centres on the cruel tactics of a plastic surgeon who avenges his daughter's rape. Read any further and there are spoilers.
I'm told that Cruz will not be playing the daughter. Nope, she will be playing a man who has raped the daughter. So, I probably don't need to explain what form the surgeon's twisted revenge comes in. I think the true identity of Eve is kept secret for some time and the gender-reallignment in Eve's past is only revealed later.
If I understand correctly, the poor daughter is now an inmate at a mental assylum, and pops up in just a small handful of scenes. Her true identity is kept under wraps for a good long time too, I believe.
For a while this film was being referred to as Tarantula, I believe, and now it will most likely take the English title The Skin I Live In. The meaning of the first title isn't so obvious, but I think we can all see how the second is relevant.