Other shows like weeds?

Well... There's Shameless and it mixes comedy and drama really well. It doesn't have anything to do with the main plot of Weeds. Nonetheless, the family is really important and they're all fcked up (that reminds me of Weeds sometimes). Oh, it's also from Showtime!!

Top Buzzer ( https://www.youtube.com/watch?v=HVmHfuQev7s ) isn't all that similar to Weeds aside from the fact that both shows are about weed dealers, but it's pretty good. Didn't get anywhere the credit it deserved.

Pretty Little Liars is not a comedy, but has funny lines and situations in it. It is like Weeds that the main characters are not the good guys. They usually don't do the right thing/aren't squeaky clean characters/aren't good role models. However you wan to describe it. Although I will say the liars are a lot crueler and use any means necessary far more than Nancy. Nancy has never blinded a girl, after all. Still, I'd only watch up to Season 3 if you were going to watch PLL, because season 4 and 5 are laughable and not in a good way. In a 'this show has gotten so pathetic it's laughable' way.

I'm a Timelord.
Right, not pompous at all then.

Breaking Bad is like the male version of Weeds. An average dad getting deeper and deeper into danger and drug production. Could have a sense of humor, but not really a comedy.

The series that used to be paired with Weeds, Californication and Secret Diary of a Call Girl, were good companions. Californication especially has very irreverent humor (and a sprinkling of dramatic moments) and a protagonist in his 40s.

Orange is the New Black - another Jenji series that has strong female characters and lots of mischief.

Desperate Housewives is in the same dramedy vain, but definitely not as edgy as Weeds. A group of MILFs who are average moms on the outside, but get into lots of trouble, have lots of sex,and have lots of secrets.

nurse jackie has the same format .. half hour show, female lead, dark comedy.

I am alarmed no one's mentioned The Riches, which is very very similar to Weeds. Also, Huff and United States of Tara don't involve drug dealing but have similar "chaos in suburbia" tones.