Strongly recommend! Great Stuff.
The animation is quirky and very life-like, without it being too lifelike (a.k.a. Final Fantasy).
The plot, like most of Philip Dick's works, is superb. After a decade of following his works in print and on screen I could sortof vaguely guess a little but the twists are brilliant. Casting is terrific with Robert Downey (who seems to be perpetually stuck in a wisecracking character groove), Winona Ryder who's as cute as always and KEanu Reeves in a neo-noir kind of way.
Overall a great film. Definitely a must-see for sci-fi fans.