The credits dedication...
What the dedication says about "friends who have been punished too much for their crimes" (can't remember the exact wording).
Was he referring to these friends getting in trouble with the law over drug abuse, or was he saying that the physical damage caused to their bodies by simply doing something that made them feel good was unfair?
Personally i like the second point better... it seems that everything pleasurable in life comes at a high cost/risk. It doesn't seem right, why would nature punish us for feeling good? This is probably my biggest frustration in life, yet i seldom hear this point talked about.