It looks like Constantine sacrifices himself not so much to save Isabel or Angela but to save the world. We are told over and over that if Mammon breaks through to the mundane plane, then (literally) all hell will break loose on Earth. By the time Constantine cuts his wrists, he is out of other options to prevent that. His sidekick Chas is dead, Angela is helpless and Gabriel has gone rogue, conspiring with Mammon to bring him through for Gabriel's own twisted reasons. By killing himself Constantine gains the time to talk to Satan (since for him time almost stops), and he figures (correctly) that Satan will not be happy at his son's attempts to overturn the ancient settlement between heaven and hell. (He also figures that it will be Satan himself who comes to collect him, giving him the chance to talk to him at once.)
Satan himself seems a little dubious of the prospects for damning Constantine even at first (he says to Constantine: "I didn't think you'd make the same mistake twice - and you didn't"). That's why he's willing to make a side deal about Isabel. By freeing Isabel, he thinks he confirms Constantine's damnation. (Incidentally, the short pause where Satan looks up at the sky as he considers Constantine's offer seems to be so he can contact God and make sure that the deal will actually be acceptable in heaven).
Of course, it doesn't work out as Satan planned. Constantine's willingness to kill himself to save the world is genuine altruism, so far as anything in the movie tells us. Of course, sacrificing yourself for a greater good is not necessarily suicide in the moral sense. This is why Constantine starts going to heaven after Satan takes care of Gabriel and Mammon (not because of what he did for Isabel, good though that may have been). His account is finally in the clear. *Then* Satan frantically works to cure Constantine's cancer and keep him alive. That way he keeps Constantine on Earth and gets another crack at damning him.
In terms of Catholic theology (and the movie only makes even a sort of theological sense on a Catholic basis) much of the above is of course nonsense. But then -- it's a movie. On its own terms the logic makes perfect sense.
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