My theory on Reinhardt and Jared Nomak
I made a post a while back asking everyone on the board if they thought Reinhardt was in on the reaper project. No one really answered. Guess, being a huge Blade fan, I probably could answer my own question. I do not believe Reinhardt was in on the project of the reaper strain, but he didn't care. Reinhardt was a footsoldier. Reinhardt was expendable and perfectly fine with being expendable, just as long as he got to kill Blade and Whistler, or one of the two. The reason Damaskinos' familiars listened to Reinhardt as if he were Damaskinos himself when he ordered them to take Blade down after Blade blew Scud up, as well as backing Reinhardt up when Blade climbed out of the pool of blood to fight him at the end is because Reinhardt was the leader of the Bloodpack, the private army for the vampire nation and therefore the most respected member.
However, Reinhardt and Chupa both knew that Damaskinos would turn on Blade after the reapers were dead. As far as Jared Nomak, I don't believe Nyssa knew Nomak was her brother. The Reaper Strain was designed obviously. Nomak was cloned from Damaskinos' DNA and born as a fetus, just like those fetuses destroyed by Whistler at the end of the film. Nyssa was totally surprised and finally understood when Whistler showed the ring in Damaskinos' lair, the family crest. Nomak only knew about Nyssa because Damaskinos visited Nomak during the experiment prior to it going awry, telling Nomak about his sister.