Something I'd love to see next season
Lois and Peter get divorced.
Now before anybody shoots this all to crap, I think it could be a good idea. First off, I think it would refresh the show a little bit and offer a different dynamic than just the simple nuclear family does wacky things this week. Their marriage is pretty toxic most of the time, and they've cheated on each other multiple times, so it would be easy to justify.
Now obviously they can't stay divorced, but that could make it all the better for Peter to work his way into winning Lois back by the end of the season. Plus, I figure Peter would get a lot of help from Brian, which could culminate in a pretty epic Brian Vs. Quagmire fight, which has been brewing for years.
Now they probably would never do this for a whole season, which would be ideal. But maybe even a few episodes?
I traveled 500 miles to give you my seed!