How did this flop!?

I saw most of it in Chemistry today and though I thought it had a lot of potential, I think it was just too gross. I mean, they could have left out some jokes and images we didn't want to see. I mean the whole thing with Frank putting his feet on the table because he had like ingrown toenail or something....I already got the picture that he was extremely gross, but I just think it was quite disturbing sometimes.

Wow I can't believe this failed so badly. A huge loss for the studio.

Well, I gave it a 5. I saw how it could have been great but instead it was just very trendy in parts and boring in others. It could have been classic like Toy Story and spawned a sequel but but going for the Disney trendy pop-language etc. it became dated - and other things made it seem silly.

However, my wife and I kept thinking of the line, "Ralph and Chuck were tormented at school" or whatever it was - pretty funny.

It could have been great but fell short - that's why it flopped. A real shame too because it was still very good - but it did read like a biology lesson - remember those cheesy shows as a kid you had to watch on old film-reels with cassette tape sound! Ugh!

I don't remember it being a bomb. It was released in the late summer and of course, several weeks later you know what happened so maybe people weren't in the mood to see it.

Unusual and potentially off-putting subject matter, uneven quality, lack of marketing, take your pick.

Supermodels...spoiled stupid little stick figures mit poofy lips who sink only about zemselves.

I thought it was ok, but I can see how it would be forgettable. The jokes were pretty weak. Great premise and great animating, but was still lacking something.

I think you're right. This movie has a lot of potential to be a perennial animated classic, so why did it flop & get lost in the shuffle? I think the answer is all about the movie's style. It had a great concept, and it had great animation, only the overall tone didn't really stick with anybody.

I feel like this concept could have really been a hit if only executed by Disney or Pixar. Disney/Pixar often get a lot of flack for being too sugary, too childish, and too morally simplistic. Only whether or not everyone likes that sugary Disney tone, it's simply a more pleasant experience, one that audiences by & large are more willing to endure.

Osmosis Jones seems to follow the pattern of a lot of other animated movies, particularly the films from Dreamworks: get a lot of famous actors to do the voices, fill the soundtrack with pop, rap, or hip-hop numbers, and make most of the characters snide and 'hip.' Drop a few light swear words in there, and fill the script with pop culture references. The result? A sarcastic, cynical, dated little adventure that never really connects with anyone on a deeper level. It doesn't help that the movie emphasises 'gross out' humor, which simply makes everything even darker.

I'm sure Pixar has jumped the shark by now, only you have to hand it to them for making some ideas pretty charming. Rats are pretty gross, only Pixar made them charming with Ratatouille. Bugs are pretty gross, only Pixar made them charming in A Bug's Life. Well, the human body can be pretty gross too. And in the case of Osmosis Jones, Warner Brothers pretty much said, 'Let's not try & make it charming. Let's just keep it dark & gross.'

I feel that if Pixar had made a similar movie about the human body, it would be a classic on the level of Finding Nemo. In my opinion, that sense of family-friendliness, that sense of innocent adventure, while perhaps too simplistic at times, is simply a better way to capture an audience. It gets into people's hearts. Osmosis Jones could have been more friendly, and maybe people would actually remember all the clever (and sometimes ingenious) human body jokes they made. Instead, we got a rap number from Kid Rock.

Well, rats.

Too much of it was just too gross to be funny. Gross-out humour is ok, but this went too far, so far it was no longer funny. How was that zit funny? How was the toenail funny? How was it funny when he picked up the egg with feces on it and ate it? People see comedies , even comedies with gross out humour, toilet humour, zit humour, etc, to laugh, not to become ill. There were images nobody wanted to see twice, therefore, a second visit to see it was out of the question, plsu word of mouth, just killed it. The Farrelly brothers are known for going to far, but this time they went too far even for them.