My dad was a medic during the war. This is how he explained that morphine effect. Wade's wounds were internal, but probably not arterial. He was very lucid during most of the scene, including his ability to understand his wound and try to tell them what to do. If his artery was severed, he would have been very quickly losing consciousness. However, his understanding of the severity of the wound (liver destroyed), means he knew it was mortal, hence his request for more morphine. At that time, the rule regarding the morphine surrettes was one for pain, two for severe pain, and three for no more pain. Three morphine surrettes was enough to kill someone and pretty damn fast and his death was consistent with morphine. Remember, he probably was not dead when he actually lost consciousness though he likely died within minutes.
The look they gave each other was their shared understanding that "yes, we are giving him a lethal dose of morphine because he is mortally wounded, as horrible as that is".
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