Cost effective ways of destroying Azazel

I think about this everytime I watch this movie. It's frustrating because you would have to: (1) assume that only you are able to come into contact with him, therefore, you would not receive much help from others, (2) not want to hurt, injure, or kill innocents, and (3) be as absolutley sure as you could be that there were no other "transferable" creatures within roughly 760 ft.

I like the sedation idea, but I'm not sure of it's longevity if you keep him sedated. If anyone came into contact with the body, it's all for naught.

I thought of possibly using a weaponized sedative to temporarily knock Azazel unconscious. Then you could take him to an old abandoned iron quarry (or something similar) and administer a slow acting poison. Since quarries are typically very deep, most over a quarter mile, and collect water over time, he would have a hard time finding animals (fish i guess underwater) in a man-made structure such as this. And it wouldn't be extremely difficult to verify the lack of fish in such a body of water. Maybe even pre-emptively use a fish toxin just to be sure.

That's my best idea, but GREAT QUESTION!!

If such a creature as Azazel existed, it would mean that others similar to it might exist too, opposed to it, neutral or not. If you were impervious to Azazel as Denzel's character was, wouldn't you be able to attract these others' interest too in some way? If not, does it mean Azazel is somehow a solitary case? Why?
If it can enter any living creature inside a certain radius, that would imply that it could easily enter something as tiny as a worm, or an even simpler creature. I don't think the rules were that clear. But it barely survived by lodging itself into a cat, so let's presume it can't enter anything and everything.
So, how do you kill Azazel, with as minimal collateral as possible...
It likes to kill, manipulate and toy with people, but to what end?
It can change hosts at will, up to a certain radius.
It is arrogant and cunning.
People have observed and possibly tried to combat it before, since it is cataloged as a myth.
There seems to be no creature of its caliber opposing it.
Azazel never mentions any other creature of its kind. And being cocky as it was, I see no reason why it wouldn't, other than there indeed were none like it.
Since it is cataloged as a myth, yet still living, people have lost to it before. None outfoxed it throughout the eons, why?(But why did Azazel allow this trace of itself to be written down by humans? Azazel is vain or lazy? Either flaw is exploitable)
Azazel learns.
By the way, when did Azazel come into existence, under what circumstances?
....
I'd say, ideally, identify Azazel. Science Azazel. Analyze the previous hosts, find a pattern, discover how Azazel does what it does. Analyze the impervious hosts, find out what makes them as such. If Azazel experiences panic out of fear of dying, that means that it really can be annihilated. Since it has to enter a new host, upon its previous one dying, and quickly at that, it must mean that its energies dissipate. Energy cannot be created, it only changes form. Identify what energy form Azazel takes while in this transient state through experimentation. (having trapped Azazel in ideal conditions)
Azazel can be transmitted through touch, so it wouldn't lose precious energy I guess, physical contact serves as the most efficient bridge between hosts. Since it is able to store memory, it means it must have something resembling a central nervous system. Since it can be transmitted so quickly and succesfully between hosts, that would imply that it's a)highly compatible with human hosts and some other lifeforms b)well suited for transmission being organized in such a way that can be transmitted with ease.
And if it's a well organized (nomad) organism of what ever sort, it means that there must be some observable biological patterns that underly its existence as a living being. Simply put, if it exists, it must leave a trace. If it thinks, it must obey patterns. If it obeys patterns, it can be predicted.

Hobbes had the right idea, but he should have just incapacitated it somehow, inside a host. But then what, he was totally mind-effed, out of a job and allies, and nobody would've believed him. Plus he didn't know Azazel could possess lesser animals.
So what to do in his situation....
Well, he should have left some record on Azazel, he could've taped Azazel without it being aware, while Azazel was in possession of different hosts. Azazel likes to smack-talk, that would've been easy. Also, Azazel was confident enough to pull its shenanigans during broad daylight, it was also confident enough to come to Hobbes' trap, either knowing that Hobbes had something up his sleeve, or not, it was cocky enough to take him on on Hobbes' terms.
Hobbes should have discerned these character flaws of Azazel, and abused them.
To be fair, he was completely routed by that point, and crazed and probably couldn't think straight.
Even if he knew about the cat, he probably couldn't have taken Azazel on by himself. Nobody could. It would take a task force of Hobbeses governed by a dozen lab-coats. Or a biblical amount luck.
Or the Enterprise, a tricorder, lvl10 force fields and a transporter.

do the same thing Hobbes did, but in some mine shaft or under a mountain or something. Somewhere where there is nothing living. Or find some area with high radiation, Try to find a place where you can be sure there is nothing alive at all near,Then it would totally work

Sedate the host, then send them in a rocket into space. That's the only way you can be sure there won't be any life around.

There's too many insects and bacterial life on Earth, who knows what it can possess.

Throw a cat at him then lock him in a cage. Then figure something out from there

I like the nuclear strike!!

Can Azazel inhabit any living organism? If so he can inhabit microscopic organisms that can be found in air, water, wherever.

If that’s the case then ‘the only way to be sure’ is to blast his current host into space.