What is this generation's Batman & Robin?
Sure, it's easy to cite a bad superhero film but to be considered the new Batman & Robin would mean it would have to be a)part of an established, and trusted, film franchise and b)leaves a bad taste big enough that the studio has to change direction for any later installments.
My vote is X-Men Origins: Wolverine, originally designed to be a prequel to the X-Men film series that would set up sequels and spin-offs it met terrible word of the mouth that caused Fox to rethink their whole approach, and X-Men: First Class, the following X-Men based film, completely ignored everything X-Men Origins: Wolverine had established. Case in point Emma Frost, seen as a young woman( late teens, early 20's) in XO:W( Set in the 80's I believe) she's used again in First Class, set in the 60's, as a woman in her late 20's to early/mid 30's.
Every X-Men film installment since Origins has ignored it and in the case of Deadpool ridiculed it, Apocalypse re-did certain aspects to it.