How about a musical of Bullets....
Word has it that Marvin Hamlisch is making a musical of this incredibly funny film.
(I think it's a great story to be brought to life through music personally.) I hope he finishes it so the lady who should be playing Helen Sinclair (my favorite character) gets a shot-Christine Ebersole, who just took the 2007 best actress in a musical Tony for Grey Gardens. She's quite talented and really has a great sense of comedic timing.
I have other people in mind for the other roles, but she stands out as the clear Helen Sinclair. (Kristin Chenoweth as Olive comes to mind.)