He was bound to die anyway. Not letting go of his earthly life was tearing his soul apart. His hallucination with Jezzie, the drug/governmental conspiracy, the recurring back pain, the fever, and the last trip to the hellish hospital were fueled by mistakes/tragedies in his life (shown in flashbacks when his family was shown, and including his current war experience and mutilation suffered at the hands of what we later find out to be one of his comrades). Louis is, in his (possibly) drug-fueled, deathbed trip, the guardian angel who saves him from hell and teaches him how to let go of earthly matters in order for his soul to find peace.
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