How could the disease be spread thru the uncle?
How did the Uncle and the AUNT (for that matter, not sure which of them was a blood relative and which one married into the family) have the disease if it started with Titus Merrye and spread to his offspring? It's Uncle Ned I'm talking about.
How could it spread to Titus's brothers and/or sisters? That's one (of the many) huge plot gaffes in this otherwise funny film.
Of course if the bald son was the first one to actually get the disease how could there be any research into it either? Seems like they made alot of assumptions from such a small pool of subjects to study.
I assume the disease had to have been written about by the "hero" of the movie...well, at least the survivor of the movie cause nobody else was alive to do it. Who else would bother writing about a disease that only affected five people anyway?