Is "The Brain of Colonel Barham" the inspiration for "Transcendence?"
Brain links with computer, soon develops from physical brain to omnipotent mind, power grows exponentially to a god-like state, sees humans as puny and insignificant. Somehow still "loves" wife and goes on rampage to keep her, even though "he" only exists in a jar. Controls other peoples minds to do his bidding. Close enough.
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