my sister was in her grade, went to my high school

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How do you know your sister isn't just jealous of Crystal's success? Just a question. Your sister needs to let go of what happened in high school - her experience sounds exactly like mine and you need to move on from it as soon as possible.
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"I had a goldfish once"

actually there might be truth to this. I was recently watching a cast interview with the 4 leads - Allison, Stiles, Scott and Lydia and twice she cut Lydia off and said things that would be counter to what Lydia was saying making a very awkward interview. She seems like the kind of person who thinks she's always right. It was so stupid too - about an edible cake that's made into a mutilated foot and Lydia was trying to explain that its edible and the cast loves it and Crystal Reed kept interrupting and going "NOOO its not" or "Its creepy"....like stfu you got your 5 mins now let the other girl speak. I don't know she seems kind of manipulative and annoying. I've known so many girls who displayed the same kind of attitude so that's why I'm coming to that conclusion. I could be wrong though. Anyone else saw that interview?

I've noticed that Katie McGrath (Merlin) does the same thing and I agree with you re what they should do - STFU! The reason for my comment is that all the OP said is "she was mean to my sister". Right, great, get over it and when you meet someone like that in future, just walk away and leave them to it.

I have also encountered the same sort of people and we definitely share the same sentiments about them. I think the problem is that some people never lose the high-school attitude that I find so infuriating. They don't travel and so don't broaden their experiences and stay in a little bubble that doesn't force them to change. She'll fall on her ass when people get sick of her bitchiness and leave her out in the cold.

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"I had a goldfish once"

I did see that interview actually - Hollywood Reporter backstage at the 2012 Comic-Con, right? Crystal Reed comes off as bit like Anne Hathaway, sweet in interviews, but is probbaly cut-throat ambitious/ruthless in real life. I don't think we'll ever get to see the real her. Like Anne Hathaway you see some interviews and think "Oh she's so nice and sweet" but then you see things maybe you weren't supposed to (like off camera) and think "Mmm, maybe she ain't so sweet". I guess what I'm saying is - none of us know the real her.

Though she has said in interviews that she was a cheerleader and dated a jock - that does not bode well for NICE GIRL CRYSTAL.

I actually went to school with Crystal. She graduated with me. She was nice back in school. I still talk to her every now and again and she's still the same nice girl I remembered from high school. I don't know who your sister is, but I would honestly have to say she's just jealous of Crystal and her success. And y'all are going to agree and says she's a bitch becuase of one interview you seen her in? Trust me, she's a very nice person to talk to.

It all depends. I mean, no-one is nice to everyone and if the OP's sis was the bullied girl, most of the popular ones get caught up in that too. I guess none of us want to consider the possibility that some of those pretty people we see on screen have bad sides too.

I have seen more than one interview where she is constantly cutting into people talking, so as to draw attention to herself. I've gotten the impression from that, that she isn't very sweet. Holland Roden is the main one she cuts off btw. So if you think she's so sweet, either you just know that side or you might be one of her kind.